fred; interpro identifier ipr036056  (InterPro Inc)

Journal: Nature Communications

Article Title: Nuclear genome of Bulinus truncatus , an intermediate host of the carcinogenic human blood fluke Schistosoma haematobium

doi: 10.1038/s41467-022-28634-9

Figure Lengend Snippet: Comparison of the features of the draft genome of Bulinus truncatus (Btru.v1) with that of Biomphalaria glabrata GCF_000457365.1_ASM45736v1 12 .

Article Snippet: A group of lectin-like proteins, homologous to fibrinogen-related proteins of Bi. glabrata (FReD; InterPro identifier IPR036056), were also inferred for Bu. truncatus ( n = 130).

Techniques: Comparison

Journal: Nature Communications

Article Title: Nuclear genome of Bulinus truncatus , an intermediate host of the carcinogenic human blood fluke Schistosoma haematobium

doi: 10.1038/s41467-022-28634-9

Figure Lengend Snippet: Synteny and contiguity of the genome (Btru.v1) of Bulinus truncatus with the draft genome of Biomphalaria glabrata and the chromosomal-level reference genomes of each Achatina immaculata and Pecten maximus , respectively. Scaffolds are arranged in circular (circos) plots with reference scaffolds for Ac. immaculata or P. maximus linked to inferred syntenic blocks of the Bu. truncatus genome using distinctly-coloured bars. Linked syntenic blocks between scaffolds of Bu. truncatus and Bi. glabrata are shown (light blue). a Synteny between the reference genomes of Bu. truncatus and Bi. glabrata established based on the positions of 595 syntenic blocks each containing three or more single-copy orthologs (i.e. 4047 of a total of 11,051). b Synteny between the reference genomes of Bu. truncatus and Ac. immaculata , established based on the positions of mapped Bu. truncatus proteins in 243 syntenic blocks each containing six or more single-copy orthologs (i.e. 2234 of a total of 8517). c Synteny between the reference genome of Bu. truncatus and P. maximus established based on the position of 291 syntenic blocks containing three or more single-copy orthologs (i.e. 1139 of a total of 4685).

Article Snippet: A group of lectin-like proteins, homologous to fibrinogen-related proteins of Bi. glabrata (FReD; InterPro identifier IPR036056), were also inferred for Bu. truncatus ( n = 130).

Techniques:

Journal: Nature Communications

Article Title: Nuclear genome of Bulinus truncatus , an intermediate host of the carcinogenic human blood fluke Schistosoma haematobium

doi: 10.1038/s41467-022-28634-9

Figure Lengend Snippet: Orthologous groups of one or more protein(s) in gastropod taxa with available gene annotation. Pecten maximus is an outgroup (bivalve). a Pairwise comparison of the orthologous groups common to Bulinus truncatus and Biomphalaria glabrata . b Genes in orthologous groups common to Bu. truncatus and Bi. glabrata . c UpSet plot of the intersections of unique or shared orthologous groups inferred from protein data sets for Bu. truncatus , Bi. glabrata , Aplysia californica , Elysia chlorotica and P. maximus . d Phylogenetic tree inferred from single copy orthologs aligned among selected gastropod taxa, including all available annotated genes. As the topology of the maximum likelihood (ML) and Bayesian inference (BI) trees was the same, the ML tree is displayed and shows nodal support values for both BI (pp) and ML (bootstrap). e Genes (annotated by KEGG) predicted to be unique to Bu. truncatus (coloured), or shared between or among the five molluscan species included here.

Article Snippet: A group of lectin-like proteins, homologous to fibrinogen-related proteins of Bi. glabrata (FReD; InterPro identifier IPR036056), were also inferred for Bu. truncatus ( n = 130).

Techniques: Comparison

Journal: Nature Communications

Article Title: Nuclear genome of Bulinus truncatus , an intermediate host of the carcinogenic human blood fluke Schistosoma haematobium

doi: 10.1038/s41467-022-28634-9

Figure Lengend Snippet: Genome-wide synteny comparisons of the genomes of Bulinus truncatus (Btru.v1), Biomphalaria glabrata (1316-R1/ASM1452496v1), Achatina immaculata and Pecten maximus in a pairwise manner.

Article Snippet: A group of lectin-like proteins, homologous to fibrinogen-related proteins of Bi. glabrata (FReD; InterPro identifier IPR036056), were also inferred for Bu. truncatus ( n = 130).

Techniques: Genome Wide

Journal: Nature Communications

Article Title: Nuclear genome of Bulinus truncatus , an intermediate host of the carcinogenic human blood fluke Schistosoma haematobium

doi: 10.1038/s41467-022-28634-9

Figure Lengend Snippet: Expansion of protein ortho-groups in Bulinus truncatus predicted to relate to snail-schistosome interactions, based on published information (see Table ). Cluster dendograms showing orthogroups for Bu. truncatus with the largest gene expansions inferred from protein data sets of Bu. truncatus , Biomphalaria glabrata , Aplysia californica , Elysia chlorotica and Pecten maximus as defined using OrthoFinder. The locations of genes linked to the Guadeloupe resistance complex (GRC) or polymorphic transmembrane cluster 2 (PTC2) are indicated (boxed).

Article Snippet: A group of lectin-like proteins, homologous to fibrinogen-related proteins of Bi. glabrata (FReD; InterPro identifier IPR036056), were also inferred for Bu. truncatus ( n = 130).

Techniques:

Journal: Nature Communications

Article Title: Nuclear genome of Bulinus truncatus , an intermediate host of the carcinogenic human blood fluke Schistosoma haematobium

doi: 10.1038/s41467-022-28634-9

Figure Lengend Snippet: a Phylogenetic relationship of a set of curated FReD-like proteins encoded in the genomes of Bu. truncatus and Bi. glabrata . Each branch tip is labelled with an existing FReD classification system for Bi. glabrata (shape) or species (colour). Posterior probability (pp) values are indicated, and groups are numbered (1 to 7). Proteins with predicted signal peptide (SP) domains are indicated with cyan boxes. A distinct colour represents each FReD class, with gene accession numbers boxed. # Bu. truncatus ortho-groups inferred from proteins of Bu. truncatus , Bi. glabrata , Aplysia californica , Elysia chlorotica and Pecten maximus (cf. Figure ). b Tertiary structure models for FReDs of Bu. truncatus employed for enhanced classification (A–F). C-terminal domain (*), as well as IgSF-like and α-helix and/or β-sheet structures, are shown.

Article Snippet: A group of lectin-like proteins, homologous to fibrinogen-related proteins of Bi. glabrata (FReD; InterPro identifier IPR036056), were also inferred for Bu. truncatus ( n = 130).

Techniques: